Toxicity Information

Toxicology was defined as the science of poisons. A fundamental principle of toxicology is “ There is no harmless substances, only harmless ways of using substances”. Today toxicology is more adequately defined as the qualitative and quantitative study of the adverse effects of toxicants on biological organisms. A toxicant can be a chemical or physical agent, including dusts, fibers, noise and radiation. The toxicity of a chemical or physical agent is a property of the agent describing its effect on biological organisms. Toxic hazard is the likelihood of damage to biological organisms based on exposure resulting from transport and other physical factors of usage. The toxic hazard of a substance can be reduced by the application of appropriate industrial hygiene techniques. The toxicity, however, cannot be changed. The toxicity information of chemicals can be found or calculated by Dose versus Response, Hodge-Sterner Table for Degree of Toxicity and Threshold Limit Values. Reference: 1. D.Crowl and J. Louvar, Chemical Process Safety: Fundamentals with Applications, Prentice Hall (2002) Chapter 2; 2. MSDS sheet from online; 3.

Management/Process Safety Information and Knowledge/Hazards Management